Alzheimer's Researcher Indicted for Data Falsification

Alzheimer's Researcher Indicted for Data Falsification

Luna Rodriguez
1 min read

Alzheimer's Researcher Indicted for Fraud in $16M NIH Funding Scandal

An Alzheimer's researcher, Hoau-Yan Wang, stands accused of falsifying data to secure $16 million in research funding from the National Institutes of Health (NIH). Collaborating with Cassava Sciences, a Texas-based pharmaceutical company, Wang's alleged misconduct has raised concerns about the integrity of scientific research and the progress of Simufilam, an Alzheimer's drug currently in Phase III trials.

Key Takeaways

  • Hoau-Yan Wang faces indictment for allegedly falsifying data to obtain $16 million in NIH funding.
  • Wang's research supported Cassava Sciences' Alzheimer's drug Simufilam, currently in Phase III trials.
  • Internal CUNY report found evidence of deliberate scientific misconduct by Wang in 14 of 31 allegations.
  • FDA inspection uncovered significant issues with Wang's analytical work for Simufilam trials.
  • Wang potentially faces up to 20 years in prison if convicted of fraud and false statements charges.


The indictment of Wang could have far-reaching consequences, impacting public trust in scientific research and disrupting funding for Alzheimer's studies. Cassava Sciences may face regulatory scrutiny and investor skepticism, potentially affecting the progress of Simufilam's Phase III trials. This scandal could also lead to increased scrutiny of NIH-funded projects and heightened pressure on academic institutions to ensure research integrity, potentially impacting biotech stocks and investor confidence in pharmaceutical R&D.

Did You Know?

  • Western Blotting:
    • Explanation: Western blotting is a widely used technique in molecular biology to detect specific proteins in a given sample of tissue homogenate. It involves gel electrophoresis, protein separation based on molecular weight, membrane transfer, and detection using specific antibodies.
  • Phase III Trials:
    • Explanation: This critical stage in drug development involves a larger patient population to confirm a drug's effectiveness, monitor side effects, and compare it with standard treatments, essential for regulatory approval.
  • National Institutes of Health (NIH):
    • Explanation: The primary federal agency responsible for supporting medical research and advancing scientific knowledge in various fields, including biomedicine and healthcare.

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